FAQs:
What is Ozempic?
Ozempic is the brand name for the drug semaglutide, which is an FDA-approved medicine that can help lower blood glucose in adults with type 2 diabetes. It belongs to a group of medications called glucagon-like peptide-1 (GLP-1). These receptor agonists mimic the GLP-1 hormone released in the gastrointestinal tract in response to eating and can prompt the body to produce more insulin and reduce appetite.
How is Ozempic Supplied (Dosage Forms)?
Ozempic is available in the following dosage forms that are injected under the skin.
1. 0.25 mg or 0.5 mg solution for injection, pre-filled pens
2. 1 mg solution for injection, pre-filled pens
3. 2 mg solution for injection, pre-filled pens (not currently marketed)
How Does Ozempic Work?
Ozempic works in several ways to lower blood sugar levels in people with type 2 diabetes. The drug also lowers heart-related risks in people with both diabetes and heart disease.
The drug does this in the following ways:
1. Ozempic mimics the actions of a naturally produced hormone called GLP-1. By activating GLP-1 receptors in your brain, Ozempic helps stimulate the pancreas to release insulin.
2. Similar to the GLP-1 hormone, Ozempic slows the movement of food through your stomach. This causes you to feel full for longer periods. In turn, it prevents a big increase in your blood sugar levels and can lead to fewer hunger cravings.
3. It increases the amount of insulin your body makes after a meal so that your blood sugar levels won’t get too high. Insulin is a hormone that lowers your blood sugar levels.
4. It lowers the amount of sugar released into your bloodstream.
Your doctor or a pharmacist can provide details about how Ozempic works in the body.
How Often Do You Take Ozempic?
You’ll inject Ozempic once each week. You should use the medication on the same day each week. And try to inject it at about the same time on each of those days.
Your doctor may start you on a low dose of Ozempic for the first 4 weeks of treatment. This way, they can see how well Ozempic is working for you. After this, your doctor will likely increase your dose. Your adjusted dose will depend on your blood sugar levels and other factors.
Each Ozempic pen holds several doses of the drug. Your doctor or pharmacist will explain when you need to throw away each pen and start using a new one.
How Should I Store Ozempic?
Before using Ozempic, store in the refrigerator between 36 F to 46 F (2 C to 8 C). Unused Ozempic can be stored until the expiration date.
Once you start using Ozempic, store at room temperature between 59 F to 86 F (15 C to 30 C) in a place that is not exposed to direct sunlight or in the refrigerator between 36 F to 46 F (2 C to 8 C) for up to 56 days. Keep the cap on the pen when you are not using Ozempic.
If you are storing Ozempic in the refrigerator, do not store the medicine next to the cooling element in the refrigerator. Do not use Ozempic if it has been frozen.
Who Can Take Ozempic?
Adults over the age of 18 years with type 2 diabetes can take Ozempic. Experts recommend that Ozempic can be prescribed to adults with type 2 diabetes when:
1. Using three medications has not been effective in managing diabetes.
2. Or you have not been able to take the medications. This might be because of side effects or because of other medical conditions.
Ozempic is only prescribed to people who have a Body Mass Index, known as BMI, of 35kg/m2 or more and have additional psychological or other medical conditions that are related to obesity. However, someone with type 2 diabetes can be prescribed Ozempic if they have a BMI below 35kg/m2 and:
1. Using insulin would affect their job due to the risk of low blood sugar, also known as hypoglycemia or hypos.
2. Weight loss would lead to improvements in other obesity-related health issues.
Who Can’t Take Ozempic?
Some medications might not be suitable for some people, which might be because of medical conditions or other reasons:
1. Your doctor will tell you to stop taking Ozempic if you develop diabetic ketoacidosis, also called DKA.
2. If you have kidney disease you might not be able to take Ozempic, but this will depend on the stage of your kidney disease.
3. If you have severe liver disease you might not be able to take Ozempic.
4. You might need to temporarily stop Ozempic if you’re going to have an operation.
5. You should not take Ozempic during pregnancy or if you are breastfeeding. If you are planning a pregnancy, it’s very important to speak to a healthcare professional if you are using this medication.
When you start a new medication always check with your healthcare team that it’s suitable for you to take.
Do You Need a Prescription for Ozempic?
Yup! Like most scripts, you can’t just add the drug to your online cart or pluck it from a drugstore shelf — you’ll need an Ozempic prescription. You can get one in person from your doctor or a board-licensed telehealth provider.
Can You Get an Ozempic Prescription Without Diabetes?
Ozempic can be prescribed “off-label” for weight loss. Off-label use means a medication is prescribed by a healthcare provider for something other than what it’s FDA-approved for, in this case, type 2 diabetes.
However off-label prescriptions are rarely covered by insurance. This is a significant barrier for many people due to the high cost of brand-name weight loss injections. If you don’t have diabetes (but are obese or overweight and have a weight-related condition like heart disease), you may be able to get a prescription for a different GLP-1 agonist. Weight loss injections that are prescribed for obesity include Wegovy (semaglutide) and Zepbound (tirzepatide).
How to Ask a Doctor for Ozempic?
If you’re someone who likes to stick to the rules, the idea of off-label drug use might feel intimidating — but it’s both legal and widely practiced. There’s no shame in asking about a medication like Ozempic if you believe it could help you.
When reaching out to your provider or any Certified Ozempic specialists, be honest about your interest. A good doctor won’t judge you for wanting to explore weight loss support. Instead, they’ll review your medical history, assess your eligibility, and help determine if Ozempic is right for you. From there, you can explore options like one-on-one Ozempic coaching, virtual Ozempic consultations, group Ozempic classes online, or even search for the best Ozempic providers near you to begin your personalized treatment plan.
How Long Does Ozempic Take to Work?
Ozempic starts to work 1 to 3 days after it’s been injected. After you start treatment with Ozempic, it may take 4 to 8 weeks to notice a difference and feel the full benefit. After at least 4 weeks at your current Ozempic dose, your doctor may increase your dose by up to 1 mg. Your dosage adjustment will depend on your current dosage and how well it’s working for you. It’s important to follow your doctor’s advice on the dose of Ozempic you should take and take it exactly as directed.
What Should I Do If I Miss a Dose Of Ozempic?
If you miss your scheduled Ozempic injection:
1. Take it within 5 days of the missed injection.
2. Skip the missed injection if more than 5 days have passed.
3. Resume your regular schedule on your next planned injection day.
How Much Does Ozempic Cost?
To put it mildly, Ozempic isn’t cheap. The list price for one Ozempic pen (which contains two to four doses) is upwards of $950, generally. Also, don’t forget to factor in the cost of continued use when crunching numbers. Ozempic and other GLP-1 agonists aren’t a one-and-done situation. You may need to take them indefinitely.
What to Know Before Taking Ozempic
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of Ozempic in the pediatric population. Safety and efficacy have not been established. Appropriate studies have not been performed on the relationship of age to the effects of Wegovy in children younger than 12 years of age. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of semaglutide injection in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, your healthcare professional must know if you are taking any of the medicines listed below. The following interactions have been selected based on their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abiraterone Acetate
- Abiraterone Acetate, Micronized
- Acarbose
- Chloroquine
- Chlorpropamide
- Ciprofloxacin
- Delafloxacin
- Enoxacin
- Gatifloxacin
- Gemifloxacin
- Glimepiride
- Glipizide
- Glyburide
- Grepafloxacin
- Hydroxychloroquine
- Insulin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Levofloxacin
- Lomefloxacin
- Metformin
- Moxifloxacin
- Nateglinide
- Norfloxacin
- Ofloxacin
- Repaglinide
- Somatrogon-ghla
- Sparfloxacin
- Tolazamide
- Tolbutamide
- Trovafloxacin
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Albiglutide
- Dulaglutide
- Exenatide
- Glecaprevir
- Liraglutide
- Lixisenatide
- Pibrentasvir
- Tirzepatide
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Depression, history of or
- Dehydration or
- Diabetic retinopathy, history of or
- Digestion problems or
- Kidney disease or
- Pancreatitis (inflammation of the pancreas), history of or
- Type 2 diabetes (for patients using Wegovy)—Use with caution. This may make these conditions worse.
- Diabetic ketoacidosis (ketones in the blood) or
- Type 1 diabetes—Should not be used in patients with these conditions. Insulin is needed to control these conditions.
- Gastroparesis (stomach does not empty food normally), severe—Use is not recommended in patients with this condition.
- Multiple endocrine neoplasia syndrome type 2 (MEN 2) or
- Thyroid cancer, history of—Should not be used in patients with these conditions.
- Surgery or other procedures that use anesthesia or deep sedation—May increase the risk of pulmonary aspiration (food or liquid getting into the lungs) during surgery or other procedures.
How to Get Ozempic with Insurance
Ideally, your insurance plan will cover your Ozempic prescription with a reasonable co-pay. However, even though you have prescription insurance, coverage will vary. If Ozempic is covered, out-of-pocket costs will vary by plan. Here are some (but not all) possible scenarios:
1. Some insurance plans will cover Ozempic for diabetes but not for weight loss.
2. Some insurance plans will cover Ozempic for either diabetes or weight loss.
3. Some insurance plans will require prior authorization to consider covering Ozempic. In this case, your healthcare provider must provide additional information to the insurance company explaining why they should cover your prescription.
Every insurance plan is different. There are several ways to find out if Ozempic is covered:
1. You can contact your health plan directly for the most recent information on coverage and pricing estimates.
2. You can use Novo Nordisk's coverage lookup tool.
3. You can have your pharmacy staff process your prescription. They can let you know if the medication is covered and help expedite the prior authorization process if necessary.
What are the Best Practices for Ozempic Use?
Managing Type 2 diabetes can feel overwhelming, but Ozempic (semaglutide), a once-weekly injection, can help you reach your treatment goals. If you're nervous about self-injections, the Ozempic pen is designed to be simple and user-friendly. With guidance and a bit of practice, most people quickly become comfortable using it. Your healthcare team will show you how, and pharmacist-recommended tips can further support your success.
A. How to Inject Ozempic
If you're unsure, your doctor or pharmacist can show you how. Here’s a simplified guide:
1. Choose an injection site:
Inject under the skin in the stomach (2" from belly button), front of the thigh, or upper arm (requires help). Rotate sites weekly.
2. Prepare supplies:
If using a new pen, take it out of the fridge 30 minutes early. You'll need:
- A new pen needle
- Alcohol swabs
- Sharps container
- Clean, dry hands
3. Attach needle:
- Remove pen cap
- Attach a new needle and remove both caps
NOTE: Never reuse needles.
4. Select dose:
Prime the pen if it’s new (your provider will explain how). Turn the selector until your dose lines up.
5. Clean skin:
Use an alcohol swab and let it dry.
6. Inject:
Insert needle, press and hold the dose button. Count to 6 after the counter shows "0" before removing.
7. Dispose:
Remove the needle and place it in a sharps container. Cap the pen if it has doses left.
B. Injection Timing
1. Inject once a week on the same day, anytime (morning or night).
2. To change your injection day, allow at least 2 days between doses and consult your provider.
C. Use With Other Medications
1. Ozempic can be taken with other medications, including insulin.
2. You may inject them in the same body area but not in the same spot.
3. Do not mix Ozempic with other injections in one syringe.
How to Get Started with Ozempic
A. Essential Preparation Before Starting Ozempic
Before beginning your Ozempic treatment, ensure you:
1. Carefully read the complete Instructions for Use on the Package Insert
2. Receive proper training from your healthcare provider on injection technique
3. Understand your prescribed dosing schedule
4. Have all necessary supplies ready.
B. Proper Injection Technique
Ozempic must be administered via subcutaneous injection (this means just under the skin) in one of these approved areas:
1. Stomach (abdomen)
2. Thigh
3. Upper arm.
Important: Never inject this medicine into a muscle or vein, as this can affect how the medication works and may be dangerous.
C. Timing and Frequency
Your weekly routine should follow these guidelines:
1. Inject 1 Ozempic injection 1 time a week on the same day
2. Choose any time of day that works best for your schedule
3. You can adjust your weekly injection day if needed, but ensure at least 2 days have passed since your last injection.
Benefits of Using Ozempic
In people with obesity, GLP-1 levels in the body are lower than normal. Ozempic is believed to help with weight loss by providing the body with more GLP-1 may help with blood sugar control and weight loss. Ozempic is believed to help with weight loss in the following ways:
1. Increases the amount of insulin available in the body
2. Helps to move sugar from the blood to be used for energy
3. Slows the movement of food through the stomach, which makes you feel full quicker
4. Tells your brain you are full, leading to a lowered appetite and consumption of fewer calories
Ozempic will not cure high blood sugar or obesity on its own. If you begin taking Ozempic, you should also incorporate other lifestyle changes, such as increasing your activity levels and eating nutritious meals in a calorie deficit.
Possible Side Effects of Ozempic
Like any medication, Ozempic (semaglutide) may cause side effects, though not everyone experiences them. It’s important to know what to expect and when to seek help if symptoms become bothersome or concerning. Understanding possible side effects can help you feel more prepared and in control of your treatment. If you’re unsure about how to manage a reaction, ask your healthcare provider — who can help with Ozempic side effects? Your doctor or pharmacist is your best resource. Ozempic may cause serious side effects, including:
1. Inflammation of your pancreas (pancreatitis). Stop using Ozempic and call your health care provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back.
2. Vision changes. Tell your healthcare provider if you have changes in vision during treatment with Ozempic.
3. Low blood sugar (hypoglycemia). Your risk of getting low blood sugar may be higher if you use Ozempic with another medicine that can cause low blood sugar, such as sulfonylurea or insulin. Signs and symptoms of low blood sugar may include: dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery.
4. Dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. You need to drink fluids to help reduce your chance of dehydration. Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away.
5. Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Ozempic. Tell your healthcare provider if you have stomach problems that are severe or will not go away.
6. Serious allergic reactions. Stop using Ozempic and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
7. Gallbladder problems. Gallbladder problems have happened in some people who take Ozempic. Tell your healthcare provider right away if you get symptoms which may include: pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools.
8. Food or liquid getting into the lungs during surgery, or other procedures that use anesthesia or deep sleepiness (deep sedation). Ozempic may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking Ozempic before you are scheduled to have surgery or other procedures.
The most common side effects of Ozempic may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.
Foods to Avoid While Taking Ozempic
There’s no “Ozempic diet” or foods and drinks you absolutely can’t eat while taking Ozempic.
But Ozempic can cause stomach upset — and other gut side effects. So you may want to avoid foods that can worsen or trigger these symptoms. You also want to avoid foods that can raise your blood sugar too quickly. This will help Ozempic and other diabetes medications better control insulin production and release. Here are five foods and drinks to avoid when taking Ozempic.
1. Foods that are High in Fat
Foods that are high in fat can worsen Ozempic side effects. On their own, these foods can lead to stomach upset. So, when they’re combined with Ozempic, the likelihood of developing gut side effects goes up. Plus, since Ozempic slows how quickly the stomach empties, these foods have even more time to hang around and upset your gut. Examples of high-fat foods include:
- Fried foods like french fries or fried chicken
- Greasy foods like pizza, cheeseburgers, and donuts
- High-fat dairy products like ice cream, butter, cream, and some cheeses
2. Sugary Foods and Drinks
If you have diabetes, you know how important it is to limit sugary foods and beverages. Foods with a high glycemic index make it harder to control blood sugar. High-sugar foods to cut back on include:
- Baked goods like cake and cookies
- Candy
- Soda
- Juice and sweetened drinks
Some foods have a surprisingly high amount of added sugar. Make sure to check food labels so you don’t eat or drink something that has more sugar than you expected.
3. Ultra-Processed Carbohydrates
Carbohydrates are an important part of a healthy diet. But not all carbohydrates are good for you. Ultra-processed carbohydrates, or refined carbohydrates, lack fiber and most vitamins. And they can cause spikes in your blood sugar levels, which can make it harder for Ozempic to do its job. Try to limit refined carbohydrates, like:
- White bread
- White rice
- White flour
- Crackers
4. Starchy Vegetables
Vegetables are an important part of a healthy diet. However starchy vegetables have a high glycemic load, which can affect blood sugar levels. You don’t have to ditch starchy vegetables completely. But try to limit how much of them you eat. This will help Ozempic work at its best. Some examples of vegetables with a higher glycemic load include:
- Potatoes
- Corn
- Parsnips
- Rutabaga
5. Alcohol
If you’re taking Ozempic, it’s a good idea to limit alcohol or avoid it altogether. Alcohol irritates the stomach. Ozempic gives alcohol more time to linger in the stomach, increasing the chances of stomach upset and nausea. Combining alcohol with diabetes medications, including Ozempic, also raises your risk of developing low blood sugar (hypoglycemia). Hypoglycemia can be dangerous to your health.
Foods to Eat While Taking Ozempic
Now that you know which foods to avoid while taking Ozempic, let’s look at some Ozempic-friendly foods. These foods can help you get the most out of your Ozempic treatment. And they can lower your chances of developing unpleasant Ozempic-related side effects. Try adding the following foods to your daily diet.
1. Lean Protein
Lean protein contains unsaturated, or healthy, fats. They’re also a great source of protein and other important nutrients. Your appetite will be lower while taking Ozempic. So it’s important to prioritize foods that are high in important nutrients like healthy fats, protein, and vitamins.
Examples of lean protein include:
- Fish
- Chicken
- Turkey
- Beans
- Tofu
2. Low-Fat Dairy Products
Like lean protein, dairy products contain proteins and vitamins. But you may want to opt for low-fat dairy products, because full-fat dairy may upset your stomach while taking Ozempic.
Examples of low-fat dairy products include:
- Low-fat milk
- Cottage cheese
- Greek yogurt
- Seeds and nuts
Seeds and nuts are another great source of healthy fats and minerals. They’re calorie-dense, but you’ll be less likely to overeat while taking Ozempic. Seeds and nuts are also a great option if you’re looking for a plant-based source for these key nutrients.
3. Low-Glycemic Fruits And Vegetables
Fruits and vegetables that have a low glycemic index are less likely to cause rapid changes in blood sugar levels. This can help Ozempic work better to control blood sugar.
Non-starchy vegetables include:
- Leafy greens
- Tomatoes
- Radishes
- Carrots
Low-glycemic fruits include:
- Fresh berries
- Apples
- Citrus fruits
Tips to Avoid Ozempic Side Effects
It’s not just what you eat that can trigger side effects from Ozempic: How you eat matters too. Here are some other eating tips to help lower your chances of experiencing Ozempic side effects:
1. Take Ozempic before meals instead of after meals.
2. If you’re eating carbs, add in some protein. This can balance your blood sugar.
3. Avoid dairy and fat in the evenings, since this can lower the chances of overnight nausea, heartburn, and belching from Ozempic.
4. Eat slowly, as this can help prevent stomach upset from slowed emptying.
5. If you’re constipated from Ozempic, add fiber to your diet slowly. Adding too much fiber too fast can worsen gas and bloating.
6. Opt for water and unsweetened drinks, as these will keep you hydrated without increasing your blood sugar.
Tips on How to Get Ozempic Near Me
The safest way to get Ozempic is by obtaining a prescription from a licensed healthcare provider and filling it at a trusted local or online pharmacy. Be cautious of offers that seem unusually cheap or promise Ozempic without a prescription — these are often scams and may be dangerous. Always avoid companies that bypass proper medical oversight.
If you're considering an online pharmacy, you can find a licensed one through the FDA’s website. According to the FDA, a legitimate online pharmacy should:
-
Require a prescription from a licensed healthcare provider
-
Have a physical U.S. address and phone number
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Employ licensed pharmacists who can answer your questions
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Be licensed with a state board of pharmacy
You might also come across ads for compounded semaglutide (a modified version of the drug mixed with other substances). The FDA advises against using these due to risks such as:
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Lack of FDA review for safety and effectiveness
-
Slightly different ingredients than the approved medication
-
Reports of adverse effects from compounded products
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Discovery of counterfeit semaglutide online, which may contain incorrect or harmful ingredients
For those seeking Ozempic diabetes management or Ozempic side effects guidance beyond medication, including where to find Ozempic diet and lifestyle coaching, speak with your healthcare provider or pharmacist — they can connect you with trusted resources to support your treatment plan.
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